Cameroon head out of the tournament finishing bottom of the group and having claimed a solitary point thanks to their opening game draw against Australia, but boss Hugo Broos will reflect on a tournament at which his side showed promise in many aspects, but ultimately lacked the quality and cutting edge to overcome their opponents.
Ernest Mabouka was sent off for a high boot after 64 minutes, and Werner doubled the lead shortly after.
Chile reached the Confederations Cup semi-finals on Sunday with a 1-1 draw against Australia, who muscled the South Americans out of their stride but exited the tournament after wasting their chances.
It was also a landmark for Joachim Loew, as Germany won 100th game with him as the head coach.
The result means Low's men progress as Group B winners and return to Sochi's Fisht Stadium on Thursday to face Mexico in the semi-finals.
It's a much bigger match for Mexico, who are curious to see how they fare against the world's elite.
Cameroon goalkeeper Fabrice Ondoa prevented Germany from extending its lead by blocking Kimmich's shot from a tight angle.
Even then the referee didn't come up with the right decision and flipped the colour of Siani's card from yellow to red. Cameroon did not give in, however, and Aboubakar restored some pride for his side with a header Ter Stegen perhaps should have saved.
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He also said that five people who had been reported missing after the incident have been found safe and well. Emergency service workers bowed their heads in respect to the victims of the catastrophic blaze.
"He has a killer instinct", Loew said.
The best chance of a tight first-half fell to Germany's Joshua Kimmich as he headed wide from six yards with the goal gaping.
"Unfortunately we went behind after a bad pass, that kind of mistake is punished, but the team's reaction was very good", said Loew.
"When the whistle goes we'll start and we'll try to match their intensity, match their work rate, match their emphasis on trying to dominate the game and see where that takes us".
Indeed, FIFA President Gianni Infantino felt confident to proclaim video review was "the future of football" and still on track to be approved by the guardians of the game's laws before the 2018 World Cup.
Cameroon would have felt more comfortable playing this match against the world number one, if they had defeated Australia in their last match which ended up in a 1-1 draw.
Today at 4 pm CET, Cameroon faces Germany in the last game of the group stage of the Confederations Cup and will attempt to pull off a qualification which seems very hard.
Roldan initially booked, then sent off, the wrong player in Sebastien Siani, before utilising the video assistant referee to determine that it was in fact Mabouka who required a red card.
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