Real boss Zinedine Zidane made a raft of changes for this tie and he almost paid the price, only for Isco to secure his side a late victor. "We will need to use all our quality".
In the Champions League, the defending European champions haven't lost at home in 12 consecutive matches, winning nine of the last 10.
"Of the three (injured), Lewandowski has the better chance of being fit to play", said Bayern manager Carlo Ancelotti.
"Lewandowski's presence will help us", Ancelotti said.
"[Isco] has been very good, he is very happy with his goals but more for the result for the team - he deserves this performance, like everyone else he has been working".
Atletico Madrid strengthened their grip on third place with a routine 3-0 win at home to Osasuna, thanks to two goals from Yannick Carrasco and Felipe Luis against a rival who failed to muster a shot on target.
While Real Madrid players were celebrating a goal by the corner flag, one of Barca's youngsters made a decision to take kick-off quickly and ran the ball down the other end of the pitch into the empty net.
"It is in the DNA of this shirt and this badge, we have shown it so many times and again today". "We'll not gamble. The first leg is already in the past and we know the difficulties Bayern can create".
Doctor removed from United Airlines flight files to preserve records
Other airline veterans agree the situation should never have gotten to the point of removing a passenger against his will. If those crew members didn't get on board, a United spokeswoman said, their flight would have been canceled.
Meanwhile, they remain on course to become the first team to retain the Champions League in 27 years.
Sociedad started strongly but it was Messi who struck first in the 17th with a sharply taken blast from outside the area that streaked into the lower corner of the net.
Isco's future is now uncertain, with the 24-year-old having just over 12 months left on his current Madrid contract, and having hinted that he will consider his future this summer in search of more regular playing time.
Reflecting on the display, in which Isco boasted a team-high 95% pass accuracy, Zidane said (via Goal): "Isco played a great game". He is three short of the 100th-goal mark in the Champions League.
Real Madrid open up a six-point lead at the top of La Liga following a 3-2 victory at struggling Sporting Gijon on Saturday afternoon.
Bale has seven goals for Madrid in this campaign.
Goalkeeper Keylor Navas is also rested, whilst Dani Carvajal is suspended and central defensive duo Pepe and Raphael Varane miss out due to injury.
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