Real Madrid denied on Friday allegations their captain Sergio Ramos breached anti-doping regulations on the night of the 2017 Champions League final.
Dexamethasone is a glucocorticoid on the banned list of the World Anti-Doping Agency (WADA).
The German publication made a series of claims, as part of the Football Leaks investigation, which suggested Spain worldwide Ramos had broken anti-doping protocol on two occasions.
"3. With regard to the rest of the content in the aforementioned publication, the club will not comment on evidence it considers to be unsubstantial".
The mix-up is reported to have occurred after a Madrid doctor allegedly filled in a doping form incorrectly relating to a drug administered to Ramos before the game against Juve. If a player tests positive for dexamethasone and its use is not reported before a drug test, then it is considered a suspected case of doping and an investigation must be opened.
Both anti-inflammatory drugs are permitted under WADA rules but only if they are declared by doctors post match.
The Spaniard, along with his Real Madrid team-mates, was tested by anti-doping authorities after the clash and one month later the deputy head of the Seibersdorf doping laboratory sent a report of their findings to the headquarters of UEFA, according to Der Spiegel.
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Furthermore, the report claims Uefa kept the breach quiet and did not take any disciplinary action.
UEFA issued a denial, saying in a statement it 'strongly and categorically refutes unfounded allegations it has covered up positive doping results.
In a separate case after a game against Malaga in April this year, Der Spiegel report Ramos obstructed an anti-doping officer by showering before his drugs test, despite being warned that it was against the rules.
Testers were told Ramos had injections of betamethasone in his left knee and left shoulder, which is also banned by Wada, rather than dexamethasone.
'UEFA has informed both WADA and Federation Internationale de Football Association of all such cases as required by the WADA code and UEFA has provided all detailed information, expert reports and evidence during the handling of such cases.
The damning report continues by claiming two days after Ramos' sample had been identified, a member of UEFA's anti-doping unit reached out to the defender for an explanation.
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