The 32-year-old reached the milestone thanks to a double in the 2-1 win over Bayern Munich in the first leg of the Champions League quarterfinal on Wednesday.
Real Madrid punished Bayern's wastefulness after the restart when Christian Ronaldo restored parity after volleying home a cross from Daniel Carvajal with two minutes into the second half.
He had not scored in the Champions League in 659 minutes before Wednesday night, last finding the net in a 2-2 group stage draw with Borussia Dortmund in September past year.
Ronaldo, the four-time world player of the year, volleyed Real level at the Allianz Arena early in the second half, then reached his milestone by slotting home the victor 13 minutes from time in the first leg.
The Portugal global was presented with a commemorative shirt by Real president Florentino Perez on Thursday to mark the accomplishment, and told the club's official website: "It's a great honour to reach 100 goals in Europe. You'd have to tell me who kept doubting as it never reached me", Ronaldo said to beIN Sports when asked about his doubters.
Ronaldo reached his milestone by slotting home the victor 13 minutes from time. Zidane's side hold a 2-1 lead in the Champions League quarter-final tie. If Neuer doesn't have a day like that then maybe we could score more goals. "We will have to play another great game to get the three points".
"Even another goal would not have made that much difference".
Local pastors prepare messages of faith for Easter
I am grateful for the Jewish heritage of my beliefs and the opportunity to participate in my first Passover Seder. As Christians, we celebrate the fact that we serve a risen Savior, and that he sealed for us great hopes.
'We will see what happens after that.
Bale suffered a minor but ill-timed muscular injury in his calf that led to him being replaced by Marco Asensio in the second half of Wednesday's first-leg win against Bayern and will be given every chance to recover for the huge double-header.
"Gareth felt something at half-time and I didn't want to take any risks, he didn't feel very well, we hope it's nothing major, nothing big", said Zidane.
"I trained hard to be playing well in this final month and a half of the season", Ronaldo said. However, we're happy with our performance. We will go game by game and make decisions that way. "We came up against a goalkeeper who pulled off a lot of saves".
"We played 11 against 10 for the last 30 minutes and had a lot of possession which changed the match and the result".
Madrid travel north with just two fit centre-backs in Sergio Ramos and Nacho Fernandez, given the injuries to Pepe and Raphael Varane.
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