Madrid could have taken an even bigger advantage into next week's second leg at the Santiago Bernabeu Stadium if it hadn't missed so many chances.
Zidane told a news conference that the latest injury is another calf issue, and the Wales international's condition is now a worry as Madrid head into the most important part of the season.
Zinedine Zidane described Cristiano Ronaldo as "amazing" and hailed the Real Madrid forward's continued motivation after he made more history with his double against Bayern Munich.
"Bale will not be with us tomorrow, that's clear", Zidane said.
"We'll be monitoring his progress every day".
Striker Duje Cop is available again after injury, while Douglas and Lacina Traore should shake off niggling problems in time for Saturday's game. The more hard the game, the more we give. We hope to have him back soon.
Comedian Brother Of Eddie Murphy Has Died
Murphy was perhaps best known for his skits involving a fictionalized Rick James character on " Chappelle's Show ". One day before his death, Murphy tweeted: "One to Sleep On: Release the past to rest as deeply as possible".
Sporting Gijon are down in 18th place in La Liga, five points adrift of Leganes ahead of this weekend's fixtures.
A win for Zidane's side will consolidate their position at the top of the standings, but he accepted that Saturday's game was a potential banana skin. "We like playing these key games to win titles". I think it is just part of the club, the way that we are. Perhaps they have had difficulties throughout the season but in a single game they can do some damage.
Pepe will also be missing from both matches with two broken ribs, while Raphael Varane has a thigh injury.
Zidane said he did not plan to call on any backup from the club's Castilla reserve side, while adding that rarely used left-back Fabio Coentrao could get a runout against Sporting.
German weekly news magazine Der Spiegel said in a Friday report that it had obtained documents, through Football Leaks, that the world-known Portuguese football player, now 32, agreed to give the large sum of money to the unnamed woman after she alleged that Ronaldo raped her at a luxury hotel in Las Vegas in June 2009, when she was in her 20s.
Over exertion in the 2013-14 campaign may also have lead to his disappointing display at the World Cup Finals in Brazil, where Portugal were eliminated at the group stage, while he injured his knee in the Euro 2016 final against France. Very few players are going to achieve it.
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